Experience effective relief from severe nausea and vomiting with Cosette Pharma's Prochlorperazine Suppositories, 25 mg. Specially formulated for patients who may not be able to take oral medications, these suppositories offer prompt and efficient antiemetic effects. Packaged in a box of 12, this solution is ideal for managing the symptoms of nausea and vomiting associated with a variety of conditions, including postoperative states and chemotherapy.

Details and Features:

Brand: Cosette Pharma
Dosage Form: Suppository
Strength: 25 mg
Quantity: 12 suppositories per box
Indications: Primarily indicated for the control of severe nausea and vomiting, and for the management of schizophrenia in patients requiring prolonged treatment.
Benefits: Rapid absorption through rectal administration, making it suitable for patients with compromised gastrointestinal absorption.

Mechanism of Action:

Prochlorperazine, a derivative of phenothiazine, works primarily by blocking dopamine receptors in the central nervous system. This antagonism at the D2 receptor sites located in the chemoreceptor trigger zone and other areas within the brain is responsible for its potent antiemetic and antipsychotic effects. This results in reduced nausea and improved control over emesis (vomiting).

Directions:

1. Dosage: Use as directed by your healthcare provider. The standard dose for nausea and vomiting may vary depending on the severity of the condition and specific patient needs.
2. Administration: Gently insert one suppository into the rectum as needed. For best results, lie down for a few minutes following insertion to ensure proper absorption.
3. Storage: Keep in a cool, dry place away from direct sunlight. Ensure it is out of reach from children and pets.

Warnings:

• CNS Effects: May cause drowsiness or dizziness. Patients should be advised not to drive or operate heavy machinery until they know how the medication affects them.
  
• Anticholinergic Effects: Use with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, or other conditions worsened by anticholinergic activity.
  
• Contraindications: Known hypersensitivity to prochlorperazine or other phenothiazines, presence of coma, or significant central nervous system depression.
  
• Pediatric Use: Not recommended for use in children under 2 years or weighing less than 20 pounds.

Side Effects:

Common side effects may include:

• Drowsiness or dizziness: Most prevalent and usually diminishes as the body adjusts to the medication.
  
• Constipation: Due to anticholinergic effects.
  Blurred vision: Typically mild and resolves spontaneously.
  
• Hypotension: Low blood pressure, requiring caution in patients at risk.
  
• Extrapyramidal symptoms: Such as tremors or muscle stiffness. These are less common but require immediate medical attention if they occur.

Discover reliable relief with Cosette Pharma's Prochlorperazine Suppositories, designed to cater to patients' needs who require an alternative route to oral medication. Providing rapid onset and efficacy, these suppositories help manage symptoms efficiently, ensuring patient comfort and enhanced well-being. Always use under medical guidance for optimal results.