Methylene Blue Injection 1% is primarily used to treat methemoglobinemia, where it helps convert methemoglobin back to hemoglobin, improving oxygen delivery. It’s also used as an antidote for certain drug or chemical poisonings, assists in some diagnostic procedures, and can serve as a dye in surgeries to highlight tissues. Always consult a healthcare professional for specific guidance and usage.

BPI Labs presents Methylene Blue Injection at a 1% concentration, designed for effective treatment of methemoglobinemia. Each 10 mL single-dose vial ensures precise dosing and reliable results, crafted with high-quality standards to deliver fast and efficient therapeutic action.

Indications and Usage: Methylene Blue Injection is indicated for:

• Treatment of methemoglobinemia
• Reduction of methemoglobin levels to improve oxygen delivery to tissues

Dosage:

• Standard Dosage: Administer 1-2 mg/kg body weight intravenously over 5 minutes.
• Maximum Dosage: Repeat as necessary, not exceeding a cumulative dose of 7 mg/kg.

CDC Guidelines: CDC guidelines stress the importance of prompt diagnosis and management of methemoglobinemia, especially in occupational or drug-induced cases. Providers should use accurate methemoglobin level testing to guide therapy.

Details and Features:

• Concentration: 1% (10 mg/mL)
• Volume: 10 mL vial
• Single-Dose Vial: Ensures sterility and reduces contamination risk
• High Purity: Produced to meet strict quality standards for safety and efficacy

Mechanism of Action: Methylene Blue serves as an electron donor, converting methemoglobin to hemoglobin by enhancing the action of NADPH methemoglobin reductase, thus restoring oxygen carrying capacity.

Directions:

1. Administer intravenously over 5 minutes.
2. Monitor patient's vitals and methemoglobin levels.
3. Repeat dosing as needed, staying within recommended limits.

Warnings:

• Contraindications: Known hypersensitivity to Methylene Blue.
• G6PD Deficiency: Risk of hemolytic anemia.
• Serotonin Syndrome Risk: Caution when used with serotonergic drugs.
• Renal Impairment: Use with caution and monitor for adverse effects.

Side Effects:

• Mild nausea and vomiting
• Discoloration of urine and skin
• Pain at injection site
• Potential for serotonin syndrome when combined with certain medications

Consultation with Healthcare Professionals: Healthcare providers should evaluate each patient's condition and history before administration. This information supplements but does not replace professional medical advice.