Loperamide hydrochloride is an active pharmaceutical ingredient (API) that is used as an antidiarrheal medication. It is a synthetic opioid that acts on the gastrointestinal tract to slow down the movement of stools, resulting in improved stool consistency and reduced frequency of bowel movements. Loperamide hydrochloride is a potent and selective agonist of the μ-opioid receptor in the intestines, which decreases motility and increases the absorption of fluids and electrolytes in the body, producing a constipating effect. It is commonly used in the treatment of acute and chronic diarrhea, including travelers' diarrhea and diarrhea associated with inflammatory bowel disease or irritable bowel syndrome. The drug is available in various forms such as oral tablets, capsules, and oral solutions under different brand names, both as a prescription and over-the-counter medication.

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Loperamide hydrochloride is a medication commonly used to treat diarrhea. In compounding, it can be used to create customized formulations for patients who have specific needs or sensitivities. It may be combined with other ingredients, such as anti-inflammatory drugs or anti-motility agents, to create a more effective medication for a particular individual. This allows for a personalized approach to treatment and better management of a patient's symptoms. However, loperamide hydrochloride should only be used for compounding under the guidance and supervision of a licensed pharmacist or healthcare provider.

CAS Number: 34552-83-5

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