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KARL SCHUMACHER Anorganic Porcine Bone Mineral Cancellous (0.25 1.0mm)

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Karl Schumacher Xenograft particulate is an osteoconductive, porous, anorganic bone mineral with carbonate apatite structure derived from porcine cancellous bone
Available in jar or syringe
Highly porous€šÄö - more space available for new bone deposition
Rough surface facilitates cell adhesion and spread for bone in-growth¹
Carbonate apatite structures are better osteoconductive materials than hydroxyapatite^2,3,4
Resorption and remodeling profiles of carbonate apatite are more similar to native or normal human bone than those of synthetic materials, such as hydroxyapatite or tricalcium phosphate⁴

1. Deligianni DD, Katsala ND, Koutsoukos PG, Missirlis YF, Effect of Surface Roughness of Hydroxyapatite on Human Bone Marrow Cell Adhesion, Proliferation, Differentiation and Detachment Strength. Elsevier Biomaterials 22 (2001) 87-96. 2. Spense G., Patel N., Brooks R., Rushton N. 2009. Carbonate Substituted Hydroxyapatite: Resorption by Osteoclasts Modifi es the Osteoblastic Response. Journal of Biomedical Materials Research Part A. 3. Ellies LG, Carter JM, Natiella JR, Featherstone JDB, Nelson DGA. 1988. Quantitative Analysis of Early In Vivo Tissue Response to Synthetic Apatite Implants. J Biomed Mater Res 22:137-148. 4. Landi E., Celotti G., Logroscino G., Tampieri A. 2003. Carbonated Hydroxyapatite as Bone Substitute. Journal of the European Ceramic Society 23: 2931-2937.

WASHING INSTRUCTIONS:

Machine wash separately in cold water on a gentle cycle. Tumble dry separately on low heat. Add QE Home Wool Dryer Balls to reduce wrinkles and increases drying efficiency. Touch up with a low heat iron as needed. Do not bleach or dry clean.