Ceftriaxone Sodium for Injection by Hikma Injectables is a broad-spectrum cephalosporin antibiotic designed for the treatment of various bacterial infections. Supplied in convenient 250 mg powder vials, it offers reliable efficacy for both inpatient and outpatient settings.

Usage: Ceftriaxone is used to treat a wide range of bacterial infections, including respiratory tract infections, skin infections, urinary tract infections, gonorrhea, and meningitis. It is effective against both Gram-positive and Gram-negative bacteria.

Dosage:

• Adults: Typically, 1 to 2 grams once daily, or in divided doses, depending on the severity and type of infection.
• Pediatric: Dosage varies based on body weight and infection type, typically 50-75 mg/kg once daily.
• Always follow the healthcare provider’s specific dosage recommendations.

CDC Guidelines: The CDC emphasizes the importance of antibiotic stewardship to prevent resistance. Use Ceftriaxone according to susceptibility patterns, and complete the full course of therapy as prescribed. Proper aseptic preparation and administration are critical.

Details and Features:

• Strength: 250 mg per vial
• Packaging: 25 vials per pack
• Broad-Spectrum: Effective against a range of pathogens
• Once-Daily Dosing: Simplifies treatment regimens and enhances compliance
• IV/IM Use: Versatile administration based on patient needs

Mechanism of Action: Ceftriaxone works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It remains effective due to its resistance to many beta-lactamases.

Directions for Use:

• Reconstitute the powder with sterile water or appropriate diluent following aseptic technique.
• Administer intravenously or intramuscularly as directed by a healthcare professional.
• Store vials and reconstituted solution as specified to maintain efficacy.

Warnings:

• Contraindicated in patients with known hypersensitivity to cephalosporins or penicillins.
• Use caution in patients with a history of gastrointestinal disease, particularly colitis.
• Monitor for signs of anaphylaxis during administration.

Side Effects: Possible side effects include:

• Injection site reactions
• Diarrhea
• Rash
• Elevated liver enzymes
• Hematological changes (e.g., eosinophilia) In case of severe adverse reactions, seek medical intervention promptly.

Ceftriaxone Sodium for Injection by Hikma Injectables delivers trusted, broad-spectrum antibacterial efficacy, tailored to meet the demands of diverse clinical settings with confidence and precision.