Caldolor (ibuprofen) was the first injectable therapy approved in the United States for the treatment of both pain and fever. It is indicated in adults and pediatric (patients six months and older) as a sole treatment for the management of mild to moderate pain; as an adjunct to reduce the use of opioids in the management of moderate to severe pain; and for the reduction of fever.
Caldolor 800 mg/8 mL vials (100 mg/mL) must be diluted prior to intravenous infusion.
Use without dilution can cause hemolysis. The CALDOLOR vials should not be given as an IV bolus or IM injection.
Dilute to a final concentration of 4 mg/mL or less.
- 100 mg dose from the vial: Dilute 1 mL of CALDOLOR in at least 100 mL of diluent
- 200 mg dose from the vial: Dilute 2 mL of CALDOLOR in at least 100 mL of diluent
- 400 mg dose from the vial: Dilute 4 mL of CALDOLOR in at least 100 mL of diluent
- 800 mg dose from the vial: Dilute 8 mL of CALDOLOR in at least 200 mL of diluent
For weight-based dosing at 10 mg/kg, ensure that the concentration of CALDOLOR is 4 mg/mL or less. Diluted solutions are stable for up to 24 hours at ambient temperature (approximately 20° to 25° C) and room lighting.
Compatible Diluents:
- 0.9% sodium chloride injection USP (normal saline)
- 5% dextrose injection USP (D5W)
- Lactated Ringer’s solution
WASHING INSTRUCTIONS:
Machine wash separately in cold water on a gentle cycle. Tumble dry separately on low heat. Add QE Home Wool Dryer Balls to reduce wrinkles and increases drying efficiency. Touch up with a low heat iron as needed. Do not bleach or dry clean.
