Regadenoson Injection by Hikma is a pharmacologic stress agent used in myocardial perfusion imaging (MPI) for patients unable to undergo adequate exercise stress. This prefilled syringe offers precise administration, enhancing diagnostic accuracy for cardiac assessments.
Usage: Regadenoson is used in radionuclide myocardial perfusion imaging to evaluate coronary artery disease in patients who cannot perform physical exercise stress tests.
Dosage:
- Standard Dose: 0.4 mg administered as a rapid intravenous injection (10 seconds) followed by a saline flush.
- Do not repeat the dose within 24 hours.
CDC Guidelines: While the CDC doesn't have specific regadenoson guidelines, it underscores the importance of using diagnostic agents in controlled environments with appropriate monitoring due to potential cardiac effects.
Details and Features:
- Concentration: 0.4 mg per 5 mL
- Volume: 5 mL prefilled syringe
- Ease of Use: Prefilled for precise and straightforward administration
- Rapid Action: Provides quick onset for effective MPI
- Selective A2A Receptor Agonist: Minimizes respiratory side effects
Mechanism of Action: Regadenoson selectively activates A2A adenosine receptors, causing coronary vasodilation and increased blood flow in the heart. This mimics the effects of exercise, enabling visualization of coronary blood flow and identifying coronary artery disease through imaging.
Directions for Use:
- Administer 0.4 mg intravenously over 10 seconds.
- Follow immediately with a 5 mL saline flush.
- Ensure appropriate monitoring and emergency equipment are available.
Warnings:
- Contraindicated in patients with certain cardiac conditions, such as unstable angina or severe hypotension.
- Exercise caution in patients with chronic obstructive pulmonary disease (COPD) or asthma.
- Monitor for potential arrhythmias and hypotension.
Side Effects: Possible side effects include:
- Dyspnea
- Headache
- Flushing
- Chest discomfort
- Dizziness In case of severe adverse effects, initiate appropriate medical interventions immediately.
Regadenoson Injection by Hikma delivers reliable, rapid-onset pharmacologic stress for accurate cardiac imaging, ensuring effective cardiovascular diagnostics in patients unable to exercise.
WASHING INSTRUCTIONS:
Machine wash separately in cold water on a gentle cycle. Tumble dry separately on low heat. Add QE Home Wool Dryer Balls to reduce wrinkles and increases drying efficiency. Touch up with a low heat iron as needed. Do not bleach or dry clean.
