Introducing the Engerix-B Hepatitis B Vaccine by GSK Vaccines, a highly effective immunization solution designed to protect individuals from the hepatitis B virus. This prefilled 0.5 mL syringe offers convenience and reliability, ensuring accurate dosing for patients. Packaged as 10 syringes per box, Engerix-B is ideal for clinics and healthcare facilities dedicated to disease prevention.

Vaccine Schedule:

• Infants: Birth, 1-2 months, 6-18 months
• Children/Adolescents: 0, 1-2, and 6-18 months apart
• Adults: 0, 1, and 6 months

Dosage:

• Infants and Children (up to 19 years): 0.5 mL
• Adults (20 years and older): 1.0 mL (not in this product specification)

CDC Guidelines:

• Recommended for all infants, unimmunized children and adolescents, and adults at risk.
• Important for healthcare workers, travelers to high-risk areas, and individuals with chronic liver disease.

Benefits:

• Effective Prevention: Protects against hepatitis B infection.
• Long-term Immunity: Establishes enduring protective immunity.
• Convenient Packaging: 10 prefilled syringes ensure easy access and administration.

Features:

• Prefilled Syringe: Ensures precise dosing.
• 0.5 mL Dose: Specifically tailored for infants and children.
• Quality Assurance: Manufactured by GSK, a leader in vaccine production.

Uses:

Engerix-B is used for active immunization against the hepatitis B virus in infants, children, and adults, contributing to broader public health efforts against viral hepatitis.

Mechanism of Action:

The vaccine contains purified hepatitis B surface antigen (HBsAg) that stimulates the immune system to produce antibodies, providing protective immunity against the hepatitis B virus.

Directions:

1. Administration: Intramuscular injection (preferred sites are the anterolateral thigh for infants and the deltoid muscle for children and adults).
2. Storage: Store refrigerated at 2°C to 8°C (36°F to 46°F). Do not freeze.

Warnings:

• Do not administer to individuals with a known hypersensitivity to yeast or any component of the vaccine.
• Use with caution in individuals with latex allergies (check for latex presence in packaging).
• Ensure epinephrine is available to manage possible anaphylactic reactions.

Side Effects:

Common side effects may include:

• Injection site reactions: Pain, redness, swelling
• Systemic reactions: Fatigue, headache, fever

Serious side effects are rare but can include:

• Severe allergic reactions: Immediate medical attention required
• Neurological events: Such as Guillain-Barre syndrome (very rare)

Consult a healthcare professional to address concerns or if serious side effects occur.