Isosorbide Dinitrate Tablets by Hikma are an effective solution for the prevention and management of angina pectoris. These tablets offer a reliable option for patients seeking to reduce the frequency and severity of angina attacks through vasodilation.

Usage: Isosorbide Dinitrate is primarily used for the prophylactic treatment of angina pectoris due to coronary artery disease. It may also be used in conjunction with other medications for heart failure management.

Dosage:

• Typical Adult Dosage: 10 mg taken orally, 2 to 3 times daily. The dosing schedule should allow for a nitrate-free interval to prevent tolerance.
• Dosage should be individualized based on patient response and clinical condition.

CDC Guidelines: While the CDC does not offer specific guidelines for Isosorbide Dinitrate, it underscores the importance of managing risk factors for coronary artery disease, such as hypertension and hyperlipidemia. Patients should be monitored for adherence to therapy and lifestyle modifications.

Details and Features:

• Strength: 10 mg of Isosorbide Dinitrate per tablet
• Count: 100 tablets per bottle
• Vasodilator Effect: Reduces cardiac workload and improves oxygen delivery
• Efficient Angina Management: Helps decrease the frequency and severity of angina episodes

Mechanism of Action: Isosorbide Dinitrate acts as a vasodilator, primarily working through the release of nitric oxide. This leads to relaxation of vascular smooth muscles, particularly in veins, reducing preload and myocardial oxygen demand, thus alleviating anginal symptoms.

Directions for Use:

• Take tablets orally, with or without food, following a consistent schedule.
• Do not crush or chew tablets.
• Ensure maintenance of a nitrate-free interval to prevent tolerance.
• Follow healthcare provider instructions closely.

Warnings:

• Contraindicated in patients using phosphodiesterase inhibitors (e.g., sildenafil) due to severe hypotension risk.
• Use with caution in patients with low blood pressure or hypovolemia.
• May cause dizziness; advise caution when driving or operating machinery.

Side Effects: Common side effects may include:

• Headache
• Dizziness
• Flushing
• Hypotension
• Nausea If severe side effects occur, seek medical advice promptly.

Isosorbide Dinitrate Tablets by Hikma offer a trusted, efficient option for angina management, ensuring patient safety and enhancing quality of life through well-controlled therapeutic action.