Methylene Blue Injection is used primarily for the treatment of methemoglobinemia, a condition where methemoglobin levels are elevated in the blood, impairing the blood's ability to deliver oxygen to tissues. It's also used as a dye for certain surgical and diagnostic procedures. Additionally, methylene blue has applications as an antidote for certain types of drug or chemical poisonings and can be used in some cases for urinary tract infections and as a stain in microbiological settings. Always consult healthcare professionals for specific medical advice and guidance.
Methylene Blue Injection, offered by Meitheal Pharmaceutical, is a high-quality therapeutic solution formulated at a 5 mg/mL concentration. Each package contains five single-dose 10 mL vials, designed for the effective treatment of methemoglobinemia. The product is crafted to ensure prompt and reliable intervention, meeting rigorous quality standards.
Indications and Usage: This injection is indicated for the treatment of:
- Methemoglobinemia
- Conditions where abnormal levels of methemoglobin reduce oxygen delivery to tissues
Dosage:
- Standard Dosage: Administer 1-2 mg/kg intravenously over 5 minutes.
- Maximum Dosage: Dosage may be repeated as necessary, but total cumulative dose should not exceed 7 mg/kg.
CDC Guidelines: The CDC emphasizes timely diagnosis and management of methemoglobinemia, particularly in cases linked to chemical exposure or medications. Accurate methemoglobin measurements should guide the use of Methylene Blue.
Details and Features:
- Concentration: 5 mg/mL
- Volume: 10 mL per vial
- Packaging: 5 single-dose vials per box ensures sterility and precision
- Quality Assurance: Manufactured to meet strict standards of safety and effectiveness
Mechanism of Action: Methylene Blue acts as a redox agent, facilitating the reduction of methemoglobin to hemoglobin through NADPH methemoglobin reductase, thereby enhancing oxygen delivery.
Directions:
- Administer slowly over 5 minutes via intravenous route.
- Continuously monitor patient vitals and methemoglobin levels.
- Repeat dosing judiciously, adhering to the cumulative dose limit.
Warnings:
- Hypersensitivity: Contraindicated in patients with known allergies to Methylene Blue.
- Serotonin Syndrome Risk: Caution advised when used with serotonergic drugs.
- G6PD Deficiency: May induce hemolytic anemia; use with caution.
- Renal Impairment: Monitor closely; adjust use as necessary.
Side Effects:
- Mild gastrointestinal symptoms (nausea, vomiting)
- Localized pain at the injection site
- Discoloration of urine and skin
- Potential for serotonin syndrome when used with certain medications
Consultation with Healthcare Professionals: Ensure administration by healthcare professionals who can evaluate individual patient needs. This summary is for informational purposes and should not replace medical advice.
WASHING INSTRUCTIONS:
Machine wash separately in cold water on a gentle cycle. Tumble dry separately on low heat. Add QE Home Wool Dryer Balls to reduce wrinkles and increases drying efficiency. Touch up with a low heat iron as needed. Do not bleach or dry clean.
